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RxNews®

Valuable and timely information on drug therapy issues impacting today's health care and pharmacy environment.

May 29, 2026

Clinical Updates

Datroway® (datopotamab deruxtecan-dlnk) – New indication

May 22, 2026 - The FDA announced the approval of Daiichi Sankyo and AstraZeneca’s Datroway (datopotamab deruxtecan-dlnk), for the treatment of adult patients with unresectable or metastatic triple-negative breast cancer (TNBC) who are not candidates for PD-1/PD-L1 inhibitor therapy.

Clinical Updates

Linzess® (linaclotide) – Expanded indication

May 21, 2026 - The FDA approved AbbVie’s Linzess (linaclotide), for the treatment of functional constipation (FC) in pediatric patients 2 years of age and older.

Drug Approvals

Differin® Epiduo® Acne Gel (adapalene/benzoyl peroxide) – New over-the-counter approval

May 22, 2026 - Galderma announced the FDA approval of over-the-counter (OTC) Differin Epiduo Acne Gel (adapalene/benzoyl peroxide) 0.1%/2.5%.

Drug Approvals

Hepcludex® (bulevirtide-gmod) – New orphan drug approval

May 22, 2026 - The FDA announced the approval of Gilead’s Hepcludex (bulevirtide-gmod), for the treatment of chronic hepatitis delta virus (HDV) infection in adults without cirrhosis or with compensated cirrhosis.

Drug Recalls - Availability

Genentech – Discontinuation of Activase® (alteplase) 100 mg vial

May 21, 2026 - Genentech announced a business decision to discontinue Activase (alteplase) 100 mg vial. Activase is not being discontinued for reasons of safety or effectiveness.