Factoring in many more aspects of a patient’s life, history and biology
Patient-centric care does more than simply orient treatment around the patient. It’s a fundamental rethink of how treatment should be approached. Rather than a biomedical model (in which the best treatment is a matter of pairing medicine to biology), patient-centric care is biopsychosocial. That means it considers the patient’s1:
- Biology
- Genetics
- Immune function
- Neurochemistry
- Tumor characteristics
- Social aspects
- Socioeconomic status
- Strength of support networks
- Health literacy
- Psychological state
- Beliefs
- Coping skills
- Personality traits
Biology and medicine play a role, no doubt, but the best care plan is fine-tuned to the interplay of biology, psychology and social factors of that particular patient.
Holistic consideration of the many factors that shape someone’s cancer journey may be a potent lever for greater health equity. Consider, for instance, immune checkpoint inhibitors (ICIs), a treatment that’s attributed to the sharp decline in U.S. cancer mortality since approved by the FDA in 2011. Patient-centric cancer care applies a biopsychosocial lens to that medical innovation.
As researchers note in a 2023 Trends Cancer study, “Black patients who are treated with ICIs may experience higher rates of [immune-related adverse events] irAEs than white patients because of their enhanced immune response, but management of their irAEs may be negatively impacted by factors such as poor quality of care, racism, negative social determinants of health and other psychosocial stressors, which can lead to treatment discontinuation.”2